Exploring the Diverse Biological Properties of Cannabidiol: A Focus on Plant Growth Stimulation-Reference-Cited by-同舟云学术

Exploring the Diverse Biological Properties of Cannabidiol: A Focus on Plant Growth Stimulation

Published:2024-04-12 Issue:5 Volume:21 Page:
ISSN:1612-1872
Container-title:Chemistry & Biodiversity
language:en
Short-container-title:Chemistry & Biodiversity

Author:

Gruľová Daniela¹^ORCID,Baranová Beáta¹,Francolino Rosaria²^ORCID,Elshafie Hazem S.³^ORCID,Kiššová Zuzana⁴,Glovaťáková Alžbeta¹,De Martino Laura²^ORCID,Amato Giuseppe²^ORCID,Martino Mara²,Caputo Lucia²^ORCID,Polito Flavio²^ORCID,Manna Francesco²,Camele Ippolito³^ORCID,Tkáčiková Ľudmila⁴,De Feo Vincenzo²⁵^ORCID

Affiliation:

1. Department of Ecology Faculty of Humanities and Natural Sciences University of Presov 17. novembra 1 08001 Presov Slovakia

2. Department of Pharmacy University of Salerno Via Giovanni Paolo II, 132 84084 Fisciano Italy

3. School of Agricultural Forestry Food and Environmental Sciences University of Basilicata Via dell'Ateneo Lucano, 10 85100 Potenza Italy

4. Department of Microbiology and Immunology University of Veterinary Medicine and Pharmacy in Kosice 041 81 Kosice Slovakia

5. Institute of Food Sciences, CNR-ISA Via Roma, 64 83100 Avellino Italy

Abstract

AbstractThe aim of the current study was to compare some biological activities of edible oils enriched with 10 % of cannabidiol (CBD samples) from the Slovak market. In addition, hemp, coconut, argan, and pumpkin pure oils were also examined. The study evaluated the fatty acids content, as well as antibacterial, antifungal, antioxidant, cytotoxic, and phytotoxic activities. The CBD samples presented antimicrobial activity against the tested bacterial strains at higher concentrations (10000 and 5000 mg/L) and antifungal activity against Alternaria alternata, Penicillium italicum and Aspergillus flavus. DPPH⋅ and FRAP assays showed greater activity in CBD‐supplemented samples compared to pure oils and vitamin E. In cell lines (IPEC‐J2 and Caco‐2), a reduced cell proliferation and viability were observed after 24 hours of incubation with CBD samples. The oils showed pro‐germinative effects. The tested activities were linked to the presence of CBD in the oils.

Funder

Vedecká Grantová Agentúra MŠVVaŠ SR a SAV

Publisher

Wiley

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/cbdv.202400274

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