Evaluation of Anti‐Alzheimer Activity of Synthetic Coumarins by Combination of in Vitro and in Silico Approaches

Author:

Erdogan Orhan Ilkay1,Deniz F. Sezer Senol1,Salmas Ramin Ekhteiari2,Irmak Sule3,Acar Ozden Ozgun4,Turgut Gurbet Celik5,Sen Alaattin36,Zbancioc Ana‐Maria7,Luca Simon Vlad8,Skiba Adrianna9,Skalicka‐Woźniak Krystyna9,Tataringa Gabriela7

Affiliation:

1. Department of Pharmacognosy Faculty of Pharmacy Gazi University 06330 Ankara Turkey

2. Department of Chemistry Britannia House King's College London SE1 1DB London UK

3. Pamukkale University Faculty of Arts & Sciences Department of Biology 20070 Denizli Turkey

4. Pamukkale University Seed Breeding & Genetics Application Research Center 20070 Denizli Turkey

5. Pamukkale University Faculty of Applied Sciences Organic Agriculture Management Civril 20680 Denizli Turkey

6. Abdullah Gul University Faculty of Life and Natural Sciences Department of Molecular Biology and Genetics 38080 Kayseri Turkey

7. University of Medicine and Pharmacy Grigore T. Popa Iasi Faculty of Pharmacy Romania

8. Biothermodynamics TUM School of Life Sciences Technical University of Munich 85354 Freising Germany

9. Department of Natural Products Chemistry Medical University of Lublin 20-093 Lublin Poland

Publisher

Wiley

Subject

Molecular Biology,Molecular Medicine,General Chemistry,Biochemistry,General Medicine,Bioengineering

Reference48 articles.

1. Reconsidering and Reforming the Amyloid Cascade Hypothesis

2. H. Hampelet al. ‘Revisiting the Cholinergic Hypothesis in Alzheimer's Disease: Emerging Evidence from Translational and Clinical Research ’J. Prev. Alzheimer's Dis.2019 6 2–15.

3. Target Enzyme in Alzheimer’s Disease: Acetylcholinesterase Inhibitors

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