Dereplication Tools for <i>Rhizophora mangle</i> Extracts from Different Mangrove Areas and their Potential Against <i>Staphylococcus aureus</i>-Reference-Cited by-同舟云学术

Dereplication Tools for Rhizophora mangle Extracts from Different Mangrove Areas and their Potential Against Staphylococcus aureus

Published:2024-06-11 Issue:7 Volume:21 Page:
ISSN:1612-1872
Container-title:Chemistry & Biodiversity
language:en
Short-container-title:Chemistry & Biodiversity

Author:

da Silva Pontes Amanda Letícia¹²^ORCID,Monteiro Leal Carla³^ORCID,Pereira Lucas Manuela¹^ORCID,Caamaño Muiño da Silva Gabriela¹^ORCID,Braga Alves Peixoto João Vitor¹^ORCID,Barbosa Succar Juliana⁴^ORCID,Ribeiro Flores Vinicius⁴^ORCID,Neves Direito Ida Carolina⁴^ORCID,Ribeiro da Silva Antonio Jorge²^ORCID,de Oliveira Chaves Filipe⁵^ORCID,Eccard Fingolo Catharina¹^ORCID

Affiliation:

1. Laboratório de Tecnologia em Produtos Naturais, Departamento de Farmácia, Faculdade de Ciências Biológicas e Saúde Universidade do Estado do Rio de Janeiro (UERJ), Campus Zona Oeste, Campo Grande Av. Manuel Caldeira de Alvarenga 1.203 Rio de Janeiro, RJ 23070-200 Brazil

2. Instituto de Pesquisas de Produtos Naturais Walter Mors Universidade Federal do Rio de Janeiro (UFRJ) Av. Carlos Chagas Filho, s/n, CCS, Bloco H, Cidade Universitária Rio de Janeiro, RJ 21941-590, Brazil

3. Laboratório de Produtos Naturais e Ensaios Biológicos, Departamento de Produtos Naturais e Alimentos, Faculdade de Farmácia Universidade Federal do Rio de Janeiro (UFRJ) Rio de Janeiro, RJ 21941-902 Brazil

4. Laboratório de Pesquisa em Biotecnologia Ambiental, Faculdade de Ciências Biológicas e Saúde Universidade do Estado do Rio de Janeiro (UERJ), Campus Zona Oeste, Campo Grande Av. Manuel Caldeira de Alvarenga 1.203 Rio de Janeiro, RJ 23070-200 Brazil

5. Núcleo de Estudos em Manguezais Universidade do Estado do Rio de Janeiro (UERJ) Rua São Francisco Xavier, 524, Maracanã Rio de Janeiro, RJ 20550-900 Brazil

Abstract

AbstractRhizophora extracts have several potential biological activities, and their metabolites can be used in the pharmaceutical industry. Extracts of Rhizophora species obtained from mangroves have shown prospective activity against Staphylococcus aureus. This study aimed to investigate the chemical profile of Rhizophora mangle leaves from fringe, basin, and transition mangrove zones and their bactericidal/bacteriostatic potential against S. aureus. R. mangle leaves were collected monthly in 2018 from litterfall in three different zones of the mangrove of Guaratiba State Reserve: fringe, basin, and transition. Extracts were prepared from the material collected in October and December for LC‐HRMS/MS analysis, and dereplication was performed using a molecular library search and the classical molecular networking GNPS platform. The minimum inhibitory concentrations (MICs) of the aqueous extract of R. mangle against S. aureus were determined. No S. aureus growth was observed compared to the control for extracts collected from September to December. Different compounds were annotated in each region, yet a marked presence of phenolic compounds was noted, among them glycosylated flavonoid derivatives of quercetin and kaempferol. The results suggest bactericidal/bacteriostatic activity for extracts of R. mangle leaves collected in 2018 from three mangrove forest zones.

Publisher

Wiley

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/cbdv.202400687

Reference32 articles.

1. Methicillin-resistant Staphylococcus aureus: an overview of basic and clinical research

2. Development and application of a new mangrove vegetation index (MVI) for rapid and accurate mangrove mapping

3. INEA – Instituto Estadual do Ambiente. Reserva Biológica Estadual de Guaratiba 2021.

4. INSTITUTO CHICO MENDES DE CONSERVAÇÃO DA BIODIVERSIDADE. Atlas dos manguezais do Brasil. Instituto Chico Mendes de Conservação da Biodiversidade 2018.

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