Transcriptional repression ofAurora-Agene by wild-type p53 through directly binding to its promoter with histone deacetylase 1 and mSin3a

Author:

Yang Tsung-Ying1,Teng Chieh-Lin Jerry234,Lin Tsung-Chieh Chester5,Chen Kun-Chieh1,Hsu Shih-Lan6,Wu Chun-Chi78ORCID

Affiliation:

1. Division of Chest Medicine, Department of Internal Medicine; Taichung Veterans General Hospital, Taichung; 407 Taiwan Republic of China

2. Division of Hematology/Medical Oncology, Department of Medicine; Taichung Veterans General Hospital; Taichung, Taiwan Republic of China

3. Department of Life Science; Tunghai University; Taichung, Taiwan Republic of China

4. Faculty of Medicine; Chung Shan Medical University; Taichung Taiwan, Republic of China

5. Genomic Medicine Core Laboratory; Chang Gung Memorial Hospital; Linkou Taiwan, Republic of China

6. Department of Education & Research; Taichung Veterans General Hospital; Taichung 407 Taiwan, Republic of China

7. Institute of Medicine, Chung Shan Medical University; Taichung Taiwan, Republic of China

8. Department of Medical Research; Chung-Shan Medical University Hospital; Taichung Taiwan, Republic of China

Publisher

Wiley

Subject

Cancer Research,Oncology

Reference60 articles.

1. Aurora-A-a guardian of poles;Marumoto;Nat Rev Cancer,2005

2. Amplification/overexpression of Aurora-A in human gastric carcinoma: potential role in differentiated type gastric carcinogenesis;Kamada;Oncol Rep,2004

3. Activation and overexpression of centrosome kinase BTAK/Aurora-A in human ovarian cancer;Gritsko;Clin Cancer Res,2003

4. Amplification/overexpression of a mitotic kinase gene in human bladder cancer;Sen;J Natl Cancer Inst,2002

5. Centrosome amplification and overexpression of aurora A are early events in rat mammary carcinogenesis;Goepfert;Cancer Res,2002

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