Gene expression changes caused by the p38 MAPK inhibitor dilmapimod in COPD patients: analysis of blood and sputum samples from a randomized, placebo-controlled clinical trial
Author:
Affiliation:
1. R&D; GlaxoSmithKline; Stevenage United Kingdom
2. R&D; GlaxoSmithKline; King of Prussia Pennsylvania USA
3. University of Manchester; Medicines Evaluation Unit; University Hospital of South Manchester Foundations Trust; Manchester United Kingdom
Funder
GSK
Publisher
Wiley
Subject
General Pharmacology, Toxicology and Pharmaceutics,Neurology
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3. Acute exacerbations of chronic obstructive pulmonary disease: identification of biologic clusters and their biomarkers;Bafadhel;Am J Respir Crit Care Med,2011
4. The role of p38 mitogen-activated protein kinase in IL-1beta transcription;Baldasarre;J Immunol,1999
5. p38 and extracellular signal-regulated kinase mitogen-activated protein kinase pathways are required for nuclear factor-kappaB p65 transactivation mediated by tumor necrosis factor;Berghe;J Biol Chem,1998
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