Inhibition of Shedding of Low‐Density Lipoprotein Receptor–Related Protein 1 Reverses Cartilage Matrix Degradation in Osteoarthritis
Author:
Affiliation:
1. University of OxfordOxford UK
2. University of CambridgeCambridge UK
3. Royal Veterinary CollegeHertfordshire UK
Funder
Arthritis Research UK
Orthopaedic Research UK
Cancer Research UK
National Institute of Arthritis and Musculoskeletal and Skin Diseases
Publisher
Wiley
Subject
Immunology,Rheumatology,Immunology and Allergy
Link
https://onlinelibrary.wiley.com/doi/pdf/10.1002/art.40080
Reference34 articles.
1. Emerging targets in osteoarthritis therapy
2. Expression of ADAMTS4 (aggrecanase-1) in human osteoarthritic cartilage
3. Aggrecan degradation in human articular cartilage explants is mediated by both ADAMTS-4 and ADAMTS-5
4. Translational development of an ADAMTS-5 antibody for osteoarthritis disease modification
5. Cloning, expression, and type II collagenolytic activity of matrix metalloproteinase-13 from human osteoarthritic cartilage.
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