Potential Interplay between Dietary Saturated Fats and Genetic Variants of the NLRP3 Inflammasome to Modulate Insulin Resistance and Diabetes Risk: Insights from a Meta‐Analysis of 19 005 Individuals-Reference-Cited by-同舟云学术

Potential Interplay between Dietary Saturated Fats and Genetic Variants of the NLRP3 Inflammasome to Modulate Insulin Resistance and Diabetes Risk: Insights from a Meta‐Analysis of 19 005 Individuals

Published:2019-09-12 Issue:22 Volume:63 Page:1900226
ISSN:1613-4125
Container-title:Molecular Nutrition & Food Research
language:en
Short-container-title:Mol. Nutr. Food Res.

Author:

Murphy Aoife M.¹,Smith Caren E.²,Murphy Leanne M.³,Follis Jack L.⁴,Tanaka Toshiko⁵,Richardson Kris²,Noordam Raymond⁶,Lemaitre Rozenn N.⁷,Kähönen Mika⁸,Dupuis Josée⁹,Voortman Trudy¹⁰,Marouli Eirini¹¹,Mook‐Kanamori Dennis O.¹²,Raitakari Olli T.¹³,Hong Jaeyoung⁹,Dehghan Abbas¹⁰,Dedoussis George¹⁴,Mutsert Renée¹²,Lehtimäki Terho¹⁵,Liu Ching‐Ti⁹,Rivadeneira Fernando¹⁶,Deloukas Panagiotis¹¹,Mikkilä Vera¹⁷,Meigs James B.¹⁸¹⁹²⁰,Uitterlinden Andre¹⁶,Ikram Mohammad A.¹⁰,Franco Oscar H.¹⁰,Hughes Maria¹,O' Gaora Peadar³,Ordovás José M.²²¹²²,Roche Helen M.¹²³

Affiliation:

1. Nutrigenomics Research GroupConway Institute of Biomedical and Biomolecular SciencesUniversity College Dublin Belfield Dublin 4, D04 V1W8 Ireland

2. Jean Mayer USDA Human Nutrition Research Centre on AgingTufts University Boston MA 02111 USA

3. UCD School of Biomolecular and Biomedical ScienceConway Institute of Biomedical and Biomolecular SciencesUniversity College Dublin Belfield Dublin 4, D04 V1W8 Ireland

4. Department of MathematicsUniversity of St. Thomas Houston TX 77006‐4626 USA

5. Translational Gerontology BranchNational Institute on Aging Baltimore MD 21224 USA

6. Department of Internal MedicineSection of Gerontology and Geriatrics, Leiden University Medical Center Leiden 2333 ZA. The Netherlands

7. Department of MedicineUniversity of Washington Seattle WA 98195 USA

8. Department of Clinical PhysiologyTampere University Hospital and University of Tampere School of Medicine 33521 Tampere Finland

9. Department of BiostatisticsBoston University School of Public Health Boston MA 02130 USA

10. Department of EpidemiologyErasmus MC‐University Medical Center Postbus 2040, 3000 CA Rotterdam The Netherlands

11. William Harvey Research InstituteBarts and The London School of Medicine and DentistryQueen Mary University of London London E1 4NS UK

12. Department of Clinical Epidemiology and Department of Public Health and Primary CareLeiden University Medical Center Albinusdreef 2 2333 ZA Leiden The Netherlands

13. Department of Clinical Physiology and Nuclear MedicineTurku University Hospital, and Research Centre of Applied and Preventive Cardiovascular Medicine, University of Turku 20521 Turku Finland

14. Department of Nutrition and DieteticsSchool of Health Science and Education, Harokopio University El. Venizelou 70 17671 Athens Greece

15. Department of Clinical ChemistryFimlab Laboratories and Finnish Cardiovascular Research Center–TampereFaculty of Medicine and Life Sciences, University of Tampere Tampere 33520 Finland

16. Department of Internal MedicineErasmus University Medical Center Postbus 2040, 3000 CA Rotterdam The Netherlands

17. Division of NutritionDepartment of Food and Environmental Sciences 00014 Helsinki Finland

18. Division of General Internal MedicineMassachusetts General Hospital Boston MA 02114 USA

19. Harvard Medical School Boston MA 02115 USA

20. Broad Institute Cambridge MA 02142 USA

21. Centro Nacional de Investigaciones Cardiovasculares (CNIC) 28029 Madrid Spain

22. IMDEA Food Institute, CEI UAM + CSIC E ‐ 28049 Madrid Spain

23. Institute For Global Food SecurityQueen's University Belfast Northern Ireland

Funder

Science Foundation Ireland

Publisher

Wiley

Subject

Food Science,Biotechnology

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/mnfr.201900226

Reference74 articles.

1. Type 2 diabetes: A 21st century epidemic

2. The pathogenesis of insulin resistance: integrating signaling pathways and substrate flux

3. The cellular and signaling networks linking the immune system and metabolism in disease

4. Macrophages, Inflammation, and Insulin Resistance

5. Macrophages, Immunity, and Metabolic Disease

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