Epigallocatechin-3-gallate, a DYRK1A inhibitor, rescues cognitive deficits in Down syndrome mouse models and in humans-Reference-Cited by-同舟云学术

Epigallocatechin-3-gallate, a DYRK1A inhibitor, rescues cognitive deficits in Down syndrome mouse models and in humans

Published:2013-09-14 Issue:2 Volume:58 Page:278-288
ISSN:1613-4125
Container-title:Molecular Nutrition & Food Research
language:en
Short-container-title:Mol. Nutr. Food Res.

Author:

De la Torre Rafael¹²³,De Sola Susana¹,Pons Meritxell³⁴,Duchon Arnaud⁵,de Lagran María Martínez³⁴,Farré Magí¹⁶,Fitó Montserrat²,Benejam Bessy⁷,Langohr Klaus¹⁸,Rodriguez Joan¹,Pujadas Mitona¹²,Bizot Jean Charles⁹,Cuenca Aída¹¹⁰,Janel Nathalie¹¹,Catuara Silvina⁴,Covas Maria Isabel²,Blehaut Henri¹²,Herault Yann⁵,Delabar Jean Marie¹⁰,Dierssen Mara³⁴

Affiliation:

1. Human Pharmacology and Clinical Neurosciences Research Group-Neurosciences Program; IMIM-Hospital del Mar Research Institute; Barcelona Spain

2. Cardiovascular Risk and Nutrition Research Group-Inflammatory and Cardiovascular Disorders Program; IMIM-Hospital del Mar Research Institute; and CIBER of Physiopathology of Obesity and Nutrition (CIBEROBN); Barcelona Spain

3. University Pompeu Fabra; CEXS-UPF; Barcelona Spain

4. Center for Genomic Regulation (CRG); and CIBER de Enfermedades Raras (CIBERER); Barcelona Spain

5. Institut de Génétique et de Biologie Moléculaire et Cellulaire; Translational Medicine and Neuroscience Program, IGBMC, CNRS, INSERM, Université de Strasbourg, UMR7104, UMR964, and Institut Clinique de la Souris, ICS, GIE CERBM; Illkirch France

6. Universitat Autònoma de Barcelona (UDIMAS-UAB); Barcelona Spain

7. Fundació Catalana Síndrome de Down; Barcelona Spain

8. Department of Statistics and Operations Research; Universitat Politècnica de Catalunya; Barcelona Spain

9. Key-Obs S.A; Allée du Titane; Orléans France

10. Epidemiology of Drugs of Abuse Research Group-Epidemiology and Public Health Program; IMIM-Hospital del Mar Research Institute; Barcelona Spain

11. Adaptive Functional Biology, EAC CNRS, University Paris Diderot, Sorbonne Paris Cité; Paris France

12. Jérôme Lejeune Foundation; Paris France

Funder

Jérôme Lejeune and Reina Sofia Foundation

DURSI

Koplowitz Foundation

FRAXA Foundation