Anti-tumorigenicity of dietary α-mangostin in an HT-29 colon cell xenograft model and the tissue distribution of xanthones and their phase II metabolites

Author:

Chitchumroonchokchai Chureeporn12,Thomas-Ahner Jennifer M.23,Li Jie4,Riedl Kenneth M.256,Nontakham Jannarin7,Suksumrarn Sunit7,Clinton Steven K.238,Kinghorn A. Douglas234,Failla Mark L.12

Affiliation:

1. Department of Human Nutrition; The Ohio State University; Columbus OH USA

2. Food Innovation Center; The Ohio State University; Columbus OH USA

3. Comprehensive Cancer Center; The Ohio State University; Columbus OH USA

4. Division of Medicinal Chemistry and Pharmacognosy; The Ohio State University; Columbus OH USA

5. Department of Food Science & Technology; The Ohio State University; Columbus OH USA

6. Nutrient and Phytochemical Analytic Shared Resource; Comprehensive Cancer Center; The Ohio State University; Columbus OH USA

7. Department of Chemistry and Center of Excellence for Innovation in Chemistry, Faculty of Science; Srinakharinwirot University; Bangkok Thailand

8. Division of Medical Oncology; Department of Internal Medicine; The Ohio State University; Columbus OH USA

Funder

Ohio State University Comprehensive Cancer Center/Molecular Carcinogenesis

Thailand Research Fund

Center of Excellence for Innovation in Chemistry

Publisher

Wiley

Subject

Food Science,Biotechnology

Reference38 articles.

1. Chronic inflammatory bowel disease and cancer;Pohl;Hepato-gastroenterology,2000

2. Cancer chemoprevention and chemotherapy: dietary polyphenols and signaling pathways;Ramos;Mol. Nutr. Food Res.,2008

3. Getting ahead of the curve: phytochemicals;Sloan;Nutraceutical World,2010

4. Garcinia mangostana L: a phytochemical and pharmacological review;Obolskiy;Phytother. Res.,2009

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