Efficacy of lorlatinib treatment in ALK rearrangement lung cancer with severe symptomatic central nervous system metastases and poor performance status
Author:
Affiliation:
1. Department of Respiratory Medicine Hoshigaoka Medical Center Osaka Japan
Publisher
Wiley
Subject
General Medicine
Link
https://onlinelibrary.wiley.com/doi/pdf/10.1002/ccr3.3927
Reference10 articles.
1. Extended Survival and Prognostic Factors for Patients With ALK-Rearranged Non–Small-Cell Lung Cancer and Brain Metastasis
2. Insights into brain metastasis in patients with ALK+ lung cancer: is the brain truly a sanctuary?
3. Discovery of (10R)-7-Amino-12-fluoro-2,10,16-trimethyl-15-oxo-10,15,16,17-tetrahydro-2H-8,4-(metheno)pyrazolo[4,3-h][2,5,11]-benzoxadiazacyclotetradecine-3-carbonitrile (PF-06463922), a Macrocyclic Inhibitor of Anaplastic Lymphoma Kinase (ALK) and c-ros Oncogene 1 (ROS1) with Preclinical Brain Exposure and Broad-Spectrum Potency against ALK-Resistant Mutations
4. Lorlatinib in patients with ALK-positive non-small-cell lung cancer: results from a global phase 2 study
5. Clinical Experience With Crizotinib in Patients With Advanced ALK-Rearranged Non–Small-Cell Lung Cancer and Brain Metastases
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1. Complete and durable regression of leptomeningeal involvement during lorlatinib treatment in a patient with lung cancer;Anti-Cancer Drugs;2024-07-09
2. Novel approaches to treatment of leptomeningeal metastases;Current Opinion in Neurology;2023-10-03
3. Enteral lorlatinib after alectinib as a treatment option in anaplastic lymphoma kinase‐positive non‐small cell lung cancer with triple problems: carcinomatous meningitis, poor performance status, and dysphagia—a case report;Respirology Case Reports;2021-06-03
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