Noninvasive prenatal testing of trisomies 21 and 18 by massively parallel sequencing of maternal plasma DNA in twin pregnancies

Author:

Huang Xuan1,Zheng Jing2,Chen Min345,Zhao Yangyu6,Zhang Chunlei2,Liu Lifu2,Xie Weiwei2,Shi Shuqiong7,Wei Yuan6,Lei Dongzhu8,Xu Chenming9,Wu Qichang10,Guo Xiaoling7,Shi Xiaomei1,Zhou Yi1,Liu Qiufang211,Gao Ya211,Jiang Fuman211,Zhang Hongyun211,Su Fengxia2,Ge Huijuan2,Li Xuchao2,Pan Xiaoyu212,Chen Shengpei213,Chen Fang21415,Fang Qun1,Jiang Hui2141617,Lau Tze Kin18,Wang Wei2111516

Affiliation:

1. Fetal Medicine Center, Department of Obstetrics and Gynecology; First Affiliated Hospital of Sun Yat-sen University; Guangzhou Guangdong China

2. BGI-Shenzhen; Shenzhen China

3. Department of Fetal Medicine and Prenatal Diagnosis; the Third Affiliated Hospital of Guangzhou Medical University; Guangzhou Guangdong China

4. Obstetrics and Gynecology Institute of Guangzhou; Guangzhou Guangdong China

5. Key Laboratory for Major Obstetric Diseases of Guangdong Province; Guangzhou Guangdong China

6. Department of Gynecology and Obstetrics; Peking University Third Hospital; Beijing China

7. Maternal and Child Healthcare Hospital of Foshan; Foshan China

8. People's Hospital of Chenzhou; Hunan China

9. Key Laboratory of Reproductive Genetics; Zhejiang University; Hangzhou China

10. Maternal and Child Health Care Hospital of Xiamen; Fujian China

11. Clinical Laboratory of BGI Health, BGI-Shenzhen; Shenzhen China

12. School of Bioscience and Bioengineering; South China University of Technology; Guangzhou Guangdong China

13. Department of Biomedical Engineering; Southeast University; Nanjing China

14. Department of Biology; University of Copenhagen; Copenhagen Denmark

15. Shenzhen Key Laboratory of Transomics Biotechnologies; Shenzhen China

16. Shenzhen Engineering Key Laboratory of Birth Defects Screening; Shenzhen China

17. Guangdong Enterprise Key Laboratory of Human Diseases Genomics; Guangdong China

18. Fetal Medicine Centre, Paramount Clinic; Hong Kong

Publisher

Wiley

Subject

Genetics(clinical),Obstetrics and Gynaecology

Reference24 articles.

1. Trends in multiple births conceived using assisted reproductive technology, United States, 1997-2000;Reynolds;Pediatrics,2003

2. The rise in multiple births in the United States: who, what, when, where, and why;Luke;Clin Obstet Gynecol,2004

3. Regional variations in trends for multiple births: a population-based evaluation in France, 1972-2003;Khoshnood;Twin Res Hum Genet,2007

4. Prenatal screening for and diagnosis of aneuploidy in twin pregnancies;Audibert;J Obstet Gynaecol Can,2011

5. Screening for aneuploidy in twins and higher-order multiples: is first-trimester nuchal translucency the solution?;Odibo;Obstet Gynecol Surv,2003

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