NAFLD polygenic risk score and risk of hepatocellular carcinoma in an East Asian population

Author:

Thomas Claire E.12ORCID,Diergaarde Brenda23ORCID,Kuipers Allison L.1ORCID,Adibi Jennifer J.1ORCID,Luu Hung N.12ORCID,Chang Xuling45ORCID,Dorajoo Rajkumar67ORCID,Heng Chew‐Kiat45ORCID,Khor Chiea‐Chuen68ORCID,Wang Renwei2,Jin Aizhen9,Koh Woon‐Puay910ORCID,Yuan Jian‐Min12ORCID

Affiliation:

1. Department of Epidemiology Graduate School of Public Health University of Pittsburgh Pittsburgh Pennsylvania USA

2. UPMC Hillman Cancer Center University of Pittsburgh Pittsburgh Pennsylvania USA

3. Department of Human Genetics Graduate School of Public Health University of Pittsburgh Pittsburgh Pennsylvania USA

4. Department of Pediatrics Yong Loo Lin School of Medicine National University of Singapore Singapore Singapore

5. Khoo Teck Puat – National University Children’s Medical Institute National University Health System Singapore Singapore

6. Genome Institute of Singapore Agency for Science, Technology and Research Singapore Singapore

7. Health Services and Systems Research Duke‐NUS Medical School Singapore Singapore Singapore

8. Singapore Eye Research Institute Singapore National Eye Centre Singapore Singapore

9. Healthy Longevity Translational Research Programme Yong Loo Lin School of Medicine, National University of Singapore Singapore Singapore

10. Singapore Institute for Clinical Sciences Agency for Science Technology and Research (A*STAR) Singapore Singapore

Funder

National Institutes of Health

National Medical Research Council

National Research Foundation Singapore

Publisher

Ovid Technologies (Wolters Kluwer Health)

Subject

Hepatology

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1. Meeting the challenges of HCC post SVR in the Post-DAA Era: A Path Forward;Clinical and Molecular Hepatology;2024-06-11

2. Benefits and harms of polygenic risk scores in organised cancer screening programmes: a cost-effectiveness analysis;The Lancet Regional Health - Western Pacific;2024-03

3. MASLD co-aggregates with HCC in families-names change, fa(c)ts remain;Hepatoma Research;2023-12-29

4. Risk of Liver Cancer in MASLD: Role of Genetic Risk Scores;Current Hepatology Reports;2023-12-02

5. Germline Genetic Associations for HBCs;Cellular and Molecular Gastroenterology and Hepatology;2023-12

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