A sensitive quantitative assay for the determination of propafenone and two metabolites, 5-hydroxypropafenone and N- depropylpropafenone, in human K2EDTA plasma using LC-MS/MS with ESI operated in positive mode-Reference-Cited by-同舟云学术

A sensitive quantitative assay for the determination of propafenone and two metabolites, 5-hydroxypropafenone and N- depropylpropafenone, in human K2EDTA plasma using LC-MS/MS with ESI operated in positive mode

Published:2017-05-07 Issue:10 Volume:31 Page:e3967
ISSN:0269-3879
Container-title:Biomedical Chromatography
language:en
Short-container-title:Biomedical Chromatography

Author:

Patel Harilal¹²,Ghoghari Ashok¹,Bhatt Chandrakant¹,Shah Shaival¹,Jha Anilkumar¹,Desai Nirmal²,Srinivas Nuggehally R.¹^ORCID

Affiliation:

1. Zydus Research Centre; Bioanalytical Laboratory; Ahmedabad India

2. Department of Chemistry; St Xavier's College (Autonomous); Ahmedabad India

Funder

Cadila Healthcare Limited

Publisher

Wiley

Subject

Clinical Biochemistry,Drug Discovery,Pharmacology,Molecular Biology,General Medicine,Biochemistry,Analytical Chemistry

Link

http://onlinelibrary.wiley.com/wol1/doi/10.1002/bmc.3967/fullpdf

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4. HPLC determination of 5-hydroxypropafenone in plasma with electrochemical detection;Brode;Methods and Findings in Experimental and Clinical Pharmacology,1988

5. Studies on the analysis of propafenone by means of internal analogue standardization;Brode;Arzneimittel-Forschung,1982

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