Compartment‐specific 13 C metabolic flux analysis reveals boosted NADPH availability coinciding with increased cell‐specific productivity for IgG1 producing CHO cells after MTA treatment-Reference-Cited by-同舟云学术

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Compartment‐specific 13 C metabolic flux analysis reveals boosted NADPH availability coinciding with increased cell‐specific productivity for IgG1 producing CHO cells after MTA treatment

Published:2021-11-09 Issue:12 Volume:21 Page:832-847
ISSN:1618-0240
Container-title:Engineering in Life Sciences
language:en
Short-container-title:Eng. Life Sci.

Author:

Wijaya Andy Wiranata¹^ORCID,Verhagen Natascha¹,Teleki Attila¹,Takors Ralf¹

Affiliation:

1. Institute of Biochemical Engineering University of Stuttgart Stuttgart Germany

Publisher

Wiley

Subject

Bioengineering,Environmental Engineering,Biotechnology

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/elsc.202100057

Reference63 articles.

1. Biopharmaceutical benchmarks 2018

2. Benchmarking of commercially available CHO cell culture media for antibody production

3. Production of recombinant protein therapeutics in cultivated mammalian cells

4. Perfusion cultures require optimum respiratory ATP supply to maximize cell‐specific and volumetric productivities

5. Application of 13C flux analysis to identify high-productivity CHO metabolic phenotypes

Cited by 2 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Overexpression of peroxisome proliferator-activated receptor co-activator-1⍺ (PGC-1⍺) in Chinese hamster ovary cells increases oxidative metabolism and IgG productivity;Metabolic Engineering;2023-09

2. Metabolic Profiling of CHO Cells during the Production of Biotherapeutics;Cells;2022-06-15

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