The futuristic applications of transition metal dichalcogenides for cancer therapy

Author:

Nandy Shouvik Kumar1,Das Sattwik1,Pandey Sadanand23ORCID,Kalita Pallab4,Gupta Manoj K.5,Kabra Atul6,Wadhwa Pankaj7,Kumar Deepak8ORCID

Affiliation:

1. Department of Pharmacology, School of Pharmacy Techno India University Kolkata India

2. Department of Chemistry, College of Natural Science Yeungnam University Gyeongsan Republic of Korea

3. School of Bioengineering and Food Technology, Faculty of Applied Sciences and Biotechnology Shoolini University Solan India

4. University of Science and Technology Meghalaya Ribhoi India

5. Department of Chemistry, School of Basic Sciences Central University of Haryana Mahendergarh India

6. University Institute of Pharma Sciences Chandigarh University, Gharuan Mohali India

7. School of Pharmaceutical Sciences Lovely Professional University, Jalandhar ‐ Delhi Phagwara India

8. Department of Pharmaceutical Chemistry, School of Pharmaceutical Sciences Shoolini University Solan India

Abstract

AbstractThe second‐most common cause of death resulting from genetic mutations in DNA sequences is cancer. The difficulty in the field of anticancer research is the application of the traditional methods, which also affects normal cells. Mutations, genetic replication alterations, and chromosomal abnormalities have a direct impact on the effectiveness of anticancer drugs at different stages. Presently, therapeutic techniques utilize nanotechnology, transition metal dichalcogenides (TMDCs), and robotics. TMDCs are being increasingly employed in tumor therapy and biosensing applications due to their biocompatibility, adjustable bandgap, versatile functionality, exceptional photoelectric properties, and wide range of applications. This study reports the advancement of nanoplatforms based on TMDCs that are specifically engineered for responsive and intelligent cancer therapy. This article offers a thorough examination of the current challenges, future possibilities for theranostic applications using TMDCs, and recent progress in employing TMDCs for cancer therapy. Currently, there is significant interest in two‐dimensional (2D) TMDCs nanomaterials as ultrathin unique physicochemical properties. These materials have attracted attention in various fields, including biomedicine. Due to their inherent ability to absorb near‐infrared light and their exceptionally large surface area, significant efforts are being made to prepare multifunctional nanoplatforms based on 2D TMDCs.

Publisher

Wiley

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