Affiliation:
1. Faculty of Chemistry Warsaw University of Technology 3 Noakowskiego Street Warsaw 00‐664 Poland
2. Faculty of Chemical and Process Engineering Warsaw University of Technology Waryńskiego 1 Street Warsaw 00‐645 Poland
3. Laboratory of Polymers and Biomaterials Institute of Fundamental Technological Research Polish Academy of Sciences Pawińskiego 5B Street Warsaw 02‐106 Poland
4. Centre for Advanced Manufacturing Technologies—Fraunhofer Project Center Faculty of Mechanical Engineering Wroclaw University of Science and Technology Lukasiewicza 5 Wroclaw 50‐371 Poland
Abstract
AbstractPolymers are of great interest for medical and cosmeceutical applications. The current trend is to combine materials of natural and synthetic origin in order to obtain products with appropriate mechanical strength and good biocompatibility, additionally biodegradable and bioresorbable. Citric acid, being an important metabolite, is an interesting substance for the synthesis of materials for biomedical applications. Due to the high functionality of the molecule, it is commonly used in biomaterials chemistry as a crosslinking agent. Among citric acid‐based biopolyesters, poly(1,8‐octanediol citrate) is the best known. It shows application potential in soft tissue engineering. This work focuses on a much less studied polyester, poly(1,3‐propanediol citrate). Porous and non‐porous materials based on the synthesized polyesters are prepared and characterized, including mechanical, thermal, and surface properties, morphology, and degradation. The main focus is on assessing the biocompatibility and antimicrobial properties of the materials.
Subject
Materials Chemistry,Polymers and Plastics,Organic Chemistry