Ten years of in vitro fertilization in Indonesia: Access to infertility care in a developing country

Author:

Wiweko Budi1234ORCID,Mansyur Eliza123,Yuningsih Tita123,Sini Ivan56,Silvana Vita123,Maidarti Mila1234ORCID,Harzif Achmad Kemal1234ORCID,Pratama Gita1234ORCID,Sumapraja Kanadi1234,Muharam Raden1234ORCID,Hestiantoro Andon1234ORCID,Soebijanto Soegiharto3456,Listyasari Nurin Aisyiyah7,Sirait Batara45,Hendarto Hendy48,Djuwantono Tono49,Halim Binarwan410,Angsar Ilyas4,Abdullah Nusratuddin411,Adnyana Putra412,Widad Shofwal413,Samsulhadi Samsulhadi48,Hidayat Syarief Thaufik47,Bayuaji Hartanto49,Permadi Wiryawan49,Hendry Dedy414,Lubis Syahnural4,Iffanolida Pritta Ameilia123,Mutia Kresna123,Septyani Tri14,Siregar Fahreza Akbar123,Khairani Namira123,Jovito Axel123,Hayatunnufus Yuli123,Cahya Ni Putu123,Yulinda Dafi123,Susanto Sarah123,Azzahra Tiara Berliana123

Affiliation:

1. Human Reproductive, Infertility, and Family Planning Research Center, Indonesian Medical Education and Research Institute (IMERI), Faculty of Medicine Universitas Indonesia Jakarta Indonesia

2. Yasmin IVF Clinic Dr. Cipto Mangunkusumo General Hospital Jakarta Indonesia

3. Division of Reproductive Endocrinology and Infertility, Department of Obstetrics and Gynecology, Faculty of Medicine Universitas Indonesia Jakarta Indonesia

4. Indonesian Association for In Vitro Fertilization (IA‐IVF) Jakarta Indonesia

5. Morula IVF Jakarta Clinic Jakarta Indonesia

6. IRSI Research and Training Center Jakarta Indonesia

7. Department of Obstetrics and Gynecology, Faculty of Medicine Diponegoro University Semarang Indonesia

8. Department of Obstetrics and Gynecology, Faculty of Medicine Airlangga University Surabaya Indonesia

9. Department of Obstetrics and Gynecology, Faculty of Medicine Padjajaran University Bandung Indonesia

10. Department of Obstetrics and Gynecology, Faculty of Medicine Universitas Sumatera Utara Medan Indonesia

11. Department of Obstetrics and Gynecology, Faculty of Medicine Hasanuddin University Makassar Indonesia

12. Department of Obstetrics and Gynecology, Faculty of Medicine Udayana University Bali Indonesia

13. Department of Obstetrics and Gynecology, Faculty of Medicine Gadjah Mada University Yogyakarta Indonesia

14. Department of Obstetrics and Gynecology, Faculty of Medicine Andalas University Padang Indonesia

Abstract

AbstractObjectiveThis research was conducted to assess access to assisted reproductive technologies (ART) and the current status of the in vitro fertilization (IVF) program that have been implemented in Indonesia over the last 10 years.MethodsWe established a retrospective cohort study and descriptive analysis of the current state of access to infertility care in Indonesia. The data were collected from all IVF centers, clinics, and hospitals in Indonesia from 2011 to 2020, including the number of IVF clinics, total ART cycles, retrieved fresh and frozen embryos, average age of IVF patients, IVF pregnancy rate, and causes of infertility.ResultsThe number of reported fertility clinics in Indonesia has increased from 14 clinics in 2011 to 41 clinics by 2020. As many as 69 569 ART cycles were conducted over the past 10 years, of which 51 892 cycles used fresh embryos and 17 677 cycles used frozen embryos. The leading cause of consecutive infertility diagnosis was male infertility. Nearly half of the women who underwent IVF procedures (48.9%) were under 35 years old. The pregnancy rate outcome of women who underwent IVF ranged from 24.6% to 37.3%.ConclusionDevelopments in ART in Indonesia have led to improvements in the ART cycles performed throughout the 10 year period. The identification of key areas that require improvement can provide an opportunity to enhance access to infertility care.

Publisher

Wiley

Subject

Obstetrics and Gynecology,General Medicine

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