Genetic variation inUGTgenes modify the associations of NSAIDs with risk of colorectal cancer: Colon cancer family registry

Author:

Scherer Dominique1,Koepl Lisel M.2,Poole Elizabeth M.234,Balavarca Yesilda1,Xiao Liren2,Baron John A.5,Hsu Li2,Coghill Anna E.2,Campbell Peter T.2,Kleinstein Sarah E.26,Figueiredo Jane C.7,Lampe Johanna W.2,Buck Katharina1,Potter John D.28,Kulmacz Richard J.9,Jenkins Mark A.10,Hopper John L.10,Win Aung K.10,Newcomb Polly A.2,Ulrich Cornelia M.12,Makar Karen W.2

Affiliation:

1. Department of Preventive Oncology; National Center for Tumor Diseases and German Cancer Research Center; 69120 Heidelberg Germany

2. Public Health Sciences Division; Fred Hutchinson Cancer Research Center; Seattle WA 98109

3. Channing Laboratory; Department of Medicine; Brigham and Women's Hospital, Harvard Medical School; Boston MA 02115

4. Department of Epidemiology; Harvard School of Public Health; Boston MA 02115

5. University of North Carolina School of Medicine; Chapel Hill NC 27599

6. Department of Molecular Genetics and Microbiology; Duke University School of Medicine; Durham NC 27710

7. University of Southern California; Keck School of Medicine; Los Angeles CA 90089

8. Centre for Public Health Research; Massey University; Wellington New Zealand

9. University of Texas Health Science Center at Houston; Houston TX 77030

10. Centre for MEGA Epidemiology, School of Population & Global Health; The University of Melbourne; Melbourne VIC 3010 Australia

Publisher

Wiley

Subject

Cancer Research,Genetics

Reference54 articles.

1. The effect of copy number variation in the phase II detoxification genes UGT2B17 and UGT2B28 on colorectal cancer risk;Angstadt;Cancer,2013

2. Effects of CYP2C9*1/*13 on the pharmacokinetics and pharmacodynamics of meloxicam;Bae;Br J Clin Pharmacol,2011

3. Controlling the false discovery rate: A practical and powerful approach to multiple testing;Benjamini;Royal Stat Soc, Ser B, Methodological,1995

4. Controlling the false discovery rate in behavior genetics research;Benjamini;Behav Brain Res,2001

5. CYP2C9 and UGT1A6 genotypes modulate the protective effect of aspirin on colon adenoma risk;Bigler;Cancer Res,2001

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