Non‐adherence to heart failure medications predicts clinical outcomes: assessment in a single spot urine sample by liquid chromatography‐tandem mass spectrometry (results of a prospective multicentre study)

Author:

Gupta Pankaj1,Voors Adriaan A.2,Patel Prashanth1,Lane Dan3,Anker Stefan D.4,Cleland John G.F.56,Dickstein Kenneth7,Filippatos Gerasimos8,Lang Chim C.9,Veldhuisen Dirk J.2,Metra Marco10,Zannad Faiez11,Samani Nilesh J.12,Jones Don J.L.13,Squire Iain B.14,Ng Leong L.15

Affiliation:

1. Department of Metabolic Medicine and Chemical Pathology, University Hospitals of Leicester NHS Trust, Department of Cardiovascular Sciences University of Leicester Leicester UK

2. Department of Cardiology University of Groningen Groningen The Netherlands

3. Department of Health Sciences University of Leicester Leicester UK

4. Department of Cardiology (CVK); and Berlin Institute of Health Center for Regenerative Therapies (BCRT); German Centre for Cardiovascular Research (DZHK) partner site Berlin Charité Universitätsmedizin Berlin Berlin Germany

5. Robertson Centre for Biostatistics, Institute of Health and Wellbeing University of Glasgow, Glasgow Royal Infirmary Glasgow UK

6. National Heart & Lung Institute, Imperial College London UK

7. Medicine, University of Bergen Stavanger University Hospital Stavanger Norway

8. Cardiology, University of Cyprus, Heart Failure Unit National and Kapodistrian University of Athens, School of Medicine, Attikon, University Hospital Athens Greece

9. Division of Molecular & Clinical Medicine Ninewells Hospital and Medical School Dundee UK

10. Cardiology, ASST Spedali Civili di Brescia, Department of Medical and Surgical Specialties Radiological Sciences and Public Health, University of Brescia Brescia Italy

11. Division of Heart Failure, Hypertension and Preventive Cardiology, Department of Cardiovascular Disease, Academic Hospital (CHU) Clinical Investigation Centre (Inserm‐CHU) Nancy France

12. British Heart Foundation, Department of Cardiovascular Sciences, University of Leicester, NIHR Leicester Biomedical Research Centre Cardiovascular Unit and University Hospitals of Leicester NHS Trust Leicester UK

13. Leicester Cancer Research Centre University of Leicester Leicester UK

14. University of Leicester University Hospitals of Leicester Leicester UK

15. Department of Cardiovascular Science, University of Leicester, NIHR Leicester Biomedical Research Centre Cardiovascular Unit and University Hospitals of Leicester NHS Trust Leicester UK

Funder

European Commission

Publisher

Wiley

Subject

Cardiology and Cardiovascular Medicine

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