Synthesis of 1-(2-deoxy-?-D-ribofuranosyl)-2,4- difluoro-5-(2-halo-1-hydroxyethyl)benzenes and related derivatives: ?thymine replacement? analogs of deoxythymidine for evaluation as antiviral and anticancer agents
Author:
Publisher
Wiley
Subject
Drug Discovery
Reference34 articles.
1. 9-(2-phosphonylmethoxyethyl)adenine (PMEA) effectively inhibits retrovirus replication in vitro and simian immunodeficiency virus infection in rhesus monkeys
2. The cytostatic activity of 5-(1-azidovinyl)-2′-deoxyuridine (AzVDU) against herpes simplex virus thymidine kinase gene-transfected FM3A cells is due to inhibition of thymidylate synthase and enhanced by UV light (λ= 254 nm) exposure
3. Bromohydrin formation in dimethyl sulfoxide
4. Antiviral activity of 5-substituted pyrimidine nucleoside analogues
Cited by 2 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献
1. Radioiodination of 1-(2-deoxy-β-d-ribofuranosyl)-2,4-difluoro-5-iodobenzene (dRFIB), a putative thymidine mimic nucleoside for cell proliferation studies;Applied Radiation and Isotopes;2008-09
2. Syntheses of 5-(2-radiohaloethyl)- and 5-(2-radiohalovinyl)-2?- deoxyuridines. Novel types of radiotracer for monitoring cancer gene therapy with PET;Journal of Labelled Compounds and Radiopharmaceuticals;2003
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