Piperacillin/Tazobactam in critically ill morbidly obese patients: A case series: The first <scp>One‐Centre</scp> experience with <scp>TDM</scp>-Reference-Cited by-同舟云学术

Piperacillin/Tazobactam in critically ill morbidly obese patients: A case series: The first One‐Centre experience with TDM

Published:2023-03 Issue:3 Volume:11 Page:
ISSN:2050-0904
Container-title:Clinical Case Reports
language:en
Short-container-title:Clinical Case Reports

Author:

Mieresova M.¹²,Balazova K.¹,Kubele J.³,Cerny D.¹⁴,Halacova M.¹²

Affiliation:

1. Department of Clinical Pharmacy Na Homolce Hospital Prague Czech Republic

2. Department of Pharmacology Motol University Hospital and 2nd Faculty of Medicine, Charles University Prague Czech Republic

3. Department of Clinical Microbiology and Antibiotic Surveillance Na Homolce Hospital Prague Czech Republic

4. Institute of Pharmacology, General University Hospital and 1st Faculty of Medicine, Charles University Prague Czech Republic

Abstract

AbstractThe aim of this article is to demonstrate extreme interindividual variability of piperacilin/tazobactam (PIP/TAZO) pharmacokinetics in critically ill morbidly obese patients and to emphasize the need for the practice of routine PIP/TAZO plasma concentrations measurement in order to ensure optimal efficacy and safety of antibiotic therapy.

Publisher

Wiley

Subject

General Medicine

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/ccr3.7032

Reference19 articles.

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4. Pharmacokinetic aspects of beta‐lactam antibiotic therapy in intensive care unit patients: a one‐center experience with TDM;Sadilová K;Ceska Slov Farm,2020

5. Therapeutic drug monitoring of antimicrobials

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