2-[(Acetyloxy)methyl]-4-(acetylsulfanyl)-2-(ethoxycarbonyl)-3-oxobutyl Group: A Thermolabile Protecting Group for Phosphodiesters
Author:
Publisher
Wiley
Subject
Inorganic Chemistry,Organic Chemistry,Physical and Theoretical Chemistry,Drug Discovery,Biochemistry,Catalysis
Link
http://onlinelibrary.wiley.com/wol1/doi/10.1002/hlca.201300028/fullpdf
Reference12 articles.
1. Towards Oligonucleotide Pro-Drugs: 2,2-Bis(ethoxycarbonyl) and 2- (Alkylaminocarbonyl)-2-cyano Substituted 3-(Pivaloyloxy)Propyl Groups as Biodegradable Protecting Groups for Internucleosidic Phosphoromonothioate Linkages
2. 2,2-Bis(ethoxycarbonyl)- and 2-(Alkylaminocarbonyl)-2-cyano-Substituted 3-(Pivaloyloxy)propyl Groups as Biodegradable Phosphate Protections of Oligonucleotides
3. Synthesis and Enzymatic Deprotection of Biodegradably Protected Dinucleoside-2′,5′-monophosphates: 3-(Acetyloxy)-2,2-bis(ethoxycarbonyl)propyl Phosphoesters of 3′-O-(Acyloxymethyl)adenylyl-2′,5′-adenosines
4. 3-Acetyloxy-2-cyano-2-(alkylaminocarbamoyl)propyl Groups as Biodegradable Protecting Groups of Nucleoside 5´-mono-Phosphates
Cited by 4 articles. 订阅此论文施引文献 订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献
1. Stability of the Phosphotriester PDE6D Inhibitors;ChemistrySelect;2021-01-19
2. Stimuli-responsive oligonucleotides in prodrug-based approaches for gene silencing;Beilstein Journal of Organic Chemistry;2018-02-19
3. 2‐Pyridinyl Thermolabile Groups as General Protectants for Hydroxyl, Phosphate, and Carboxyl Functions;Current Protocols in Nucleic Acid Chemistry;2017-03
4. ChemInform Abstract: 2-[(Acetyloxy)methyl]-4-(acetylsulfanyl)-2-(ethoxycarbonyl)-3-oxobutyl Group: A Thermolabile Protecting Group for Phosphodiesters.;ChemInform;2014-02-27
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