A Novel Synthesis of Quinazolines by Cyclization of 1-(2-Isocyanophenyl)alkylideneamines Generated by the Treatment of 2-(1-Azidoalkyl)phenyl Isocyanides with NaH-Reference-Cited by-同舟云学术

A Novel Synthesis of Quinazolines by Cyclization of 1-(2-Isocyanophenyl)alkylideneamines Generated by the Treatment of 2-(1-Azidoalkyl)phenyl Isocyanides with NaH

Published:2014-06 Issue:6 Volume:97 Page:822-829
ISSN:0018-019X
Container-title:Helvetica Chimica Acta
language:en
Short-container-title:HCA

Author:

Ezaki Kosuke,Kobayashi Kazuhiro

Publisher

Wiley

Subject

Inorganic Chemistry,Organic Chemistry,Physical and Theoretical Chemistry,Drug Discovery,Biochemistry,Catalysis

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1. Development of erlotinib derivatives as CIP2A-ablating agents independent of EGFR activity

2. 4-Substituted-2-phenylquinazolines as inhibitors of BCRP

3. Synthesis, characterization, screening and docking analysis of 4-anilinoquinazoline derivatives as tyrosine kinase inhibitors

4. Design, synthesis and in vitro anti-proliferative activity of 4,6-quinazolinediamines as potent EGFR-TK inhibitors

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