Mechanistic Insights on Reduction of Carboxamides by Diisobutylaluminum Hydride and Sodium Hydride−Iodide Composite

Author:

Ong Derek Yiren1,Watanabe Kohei2ORCID,Takita Ryo2ORCID,Chiba Shunsuke1ORCID

Affiliation:

1. Division of Chemistry and Biological Chemistry, School of Physical and Mathematical SciencesNanyang Technological University Singapore 637371

2. Graduate School of Pharmaceutical SciencesThe University of Tokyo, 7-3-1 Hongo, Bunkyo-ku Tokyo 113-0033 Japan

Funder

Takeda Science Foundation

Fugaku Trust for Medicinal Research

Uehara Memorial Foundation

Publisher

Wiley

Subject

Inorganic Chemistry,Organic Chemistry,Physical and Theoretical Chemistry,Drug Discovery,Biochemistry,Catalysis

Reference21 articles.

1. M. Hudlicky ‘Reductions in Organic Chemistry’ Ellis Horwood Ltd. Chichester U. K. 1984.

2. J. Seyden-Penne ‘Reductions by the Alumino- and Borohydrides in Organic Synthesis’ Wiley New York 1997.

3. ‘Metallorganische Verbindungen, XXVII Aluminiumtrialkyle und Dialkyl-Aluminiumhydride Aus Aluminiumisobutyl-Verbindungen’;Ziegler K.;Liebigs Ann.,1960

4. P. Galatsis M. Sollogoub P. Sinaÿ ‘Diisobutylaluminum Hydride’ in ‘Encyclopedia of Reagents for Organic Synthesis’ John Wiley & Sons New York 2008.

5. ‘Applications of Diisobutylaluminium Hydride (DIBAH) and Triisobutylaluminium (TIBA) as Reducing Agents in Organic Synthesis’;Winterfeldt E.;Synthesis,1975

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