1. Department of Medicinal Chemistry, School of Pharmacy; Qingdao University; Qingdao Shandong 266021 China
2. Department of Biochemistry; Medical College, Qingdao University; Qingdao Shandong 266021 China
3. Experimental Animal Center, Medical College, Qingdao University; Qingdao Shandong 266021 China