Children with HbSβ0 thalassemia have higher hemoglobin levels and lower incidence rate of acute chest syndrome compared to children with HbSS

Author:

Day Melissa E.1ORCID,Rodeghier Mark2,DeBaun Michael R.1ORCID

Affiliation:

1. Vanderbilt-Meharry Center of Excellence in Sickle Cell Disease; Vanderbilt University Medical Center; Nashville Tennessee

2. Rodeghier Consultants; Chicago Illinois

Funder

Doris Duke Charitable Foundation

Publisher

Wiley

Subject

Oncology,Hematology,Pediatrics, Perinatology, and Child Health

Reference15 articles.

1. Sickle hemoglobin (HbS) allele and sickle cell disease: a HuGE review;Ashley-Koch;Am J Epidemiol,2000

2. Stroke prevention trial in sickle cell anemia;Adams;Control Clin Trials,1998

3. Investigators, T. O. P. S. P. i. S. C. A. T. Discontinuing prophylactic transfusions used to prevent stroke in sickle cell disease;Adams;N Engl J Med,2005

4. Controlled trial of transfusions for silent cerebral infarcts in sickle cell anemia;DeBaun;N Engl J Med,2014

5. Acute chest syndrome is associated with single nucleotide polymorphism-defined beta globin cluster haplotype in children with sickle cell anaemia;Bean;Br J Haematol,2013

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