Metabolic Stability Screen in Drug Discovery-Reference-Cited by-同舟云学术

Metabolic Stability Screen in Drug Discovery

Published:2014-01-15 Issue: Volume: Page:1-23
ISSN:
Container-title:Handbook of Metabolic Pathways of Xenobiotics
language:
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Author:

Lu Chuang¹

Affiliation:

1. Millennium: The Takeda Oncology Company; Cambridge MA USA

Publisher

John Wiley & Sons, Ltd

Reference48 articles.

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2. Substrate-dependent modulation of CYP3A4 catalytic activity: analysis of 27 test compounds with four fluorometric substrates;Stresser;Drug Metab. Dispos.,2002

3. In vitro drug interactions of cytochrome P450: an evaluation of fluorogenic to conventional substrates;Cohen;Drug Metab. Dispos.,2003

4. FDA Drug Interaction Studies - Study Design, Data Analysis, and Implications for Dosing and Labeling 2006 http://www.FDA.gov/cder/guidence/6695dft.htm

5. The conduct of in vitro studies to address time-dependent inhibition of drug metabolizing enzymes: a perspective of the pharmaceutical research and manufactures of America;Grimm;Drug Metab. Dispos.,2009

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