Divalproex
Author:
Affiliation:
1. Amgen; Cambridge MA USA
Publisher
John Wiley & Sons, Ltd
Reference15 articles.
1. Human CYP2C9 and CYP2A6 mediate formation of the hepatotoxin 4-ene-valproic acid;Sadeque;J. Pharmacol. Exp. Ther.,1997
2. Metabolic profiling of valproic acid by cDNA-expressed human cytochrome P450 enzymes using negative-ion chemical ionization gas chromatography-mass spectrometry;Anari;J. Chromatogr. B Biomed. Sci. Appl.,2000
3. Contribution of CYP2C9, CYP2A6, and CYP2B6 to valproic acid metabolism in hepatic microsomes from individuals with the CYP2C9*1/*1 genotype;Kiang;Toxicol. Sci.,2006
4. Kinetics of valproic acid glucuronidation: evidence for in vivo autoactivation;Wong;Drug Metab. Dispos.,2007
5. Effect of aging on glucuronidation of valproic acid in human liver microsomes and the role of UDP-glucuronosyltransferase UGT1A4, UGT1A8, and UGT1A10;Argikar;Drug Metab. Dispos.,2009
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