Harnessing endophenotypes and network medicine for Alzheimer's drug repurposing

Author:

Fang Jiansong12,Pieper Andrew A.34567,Nussinov Ruth89,Lee Garam10,Bekris Lynn211,Leverenz James B.12,Cummings Jeffrey1013,Cheng Feixiong21114ORCID

Affiliation:

1. Science and Technology Innovation Center Guangzhou University of Chinese Medicine Guangzhou Guangdong China

2. Genomic Medicine Institute, Lerner Research Institute, Cleveland Clinic Cleveland Ohio USA

3. Harrington Discovery Institute University Hospitals Cleveland Medical Center Cleveland Ohio USA

4. Department of Psychiatry Case Western Reserve University Cleveland Ohio USA

5. Geriatric Psychiatry GRECC, Louis Stokes Cleveland VA Medical Center Cleveland Ohio USA

6. Institute for Transformative Molecular Medicine, School of Medicine Case Western Reserve University Cleveland Ohio USA

7. Weill Cornell Autism Research Program Weill Cornell Medicine of Cornell University New York

8. Cancer and Inflammation Program Leidos Biomedical Research, Inc., Frederick National Laboratory for Cancer Research, National Cancer Institute at Frederick Frederick Maryland USA

9. Department of Human Molecular Genetics and Biochemistry, Sackler School of Medicine Tel Aviv University Tel Aviv Israel

10. Cleveland Clinic Lou Ruvo Center for Brain Health Las Vegas Nevada USA

11. Department of Molecular Medicine, Cleveland Clinic Lerner College of Medicine Case Western Reserve University Cleveland Ohio USA

12. Lou Ruvo Center for Brain Health Neurological Institute, Cleveland Clinic Cleveland Ohio USA

13. Chambers‐Grundy Center for Transformative Neuroscience, Department of Brain Health, School of Integrated Health Sciences University of Nevada Las Vegas Las Vegas Nevada USA

14. Case Comprehensive Cancer Center Case Western Reserve University School of Medicine Cleveland Ohio USA

Publisher

Wiley

Subject

Drug Discovery,Pharmacology,Molecular Medicine

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