Model-Based Approach for Optimizing Study Design and Clinical Drug Performances of Extended-Release Formulations of Methylphenidate for the Treatment of ADHD-Reference-Cited by-同舟云学术

Model-Based Approach for Optimizing Study Design and Clinical Drug Performances of Extended-Release Formulations of Methylphenidate for the Treatment of ADHD

Published:2017-09-19 Issue:6 Volume:102 Page:951-960
ISSN:0009-9236
Container-title:Clinical Pharmacology & Therapeutics
language:en
Short-container-title:Clin. Pharmacol. Ther.

Author:

Gomeni R¹,Bressolle-Gomeni FMM¹,Spencer TJ²,Faraone SV³,Fang L⁴,Babiskin A⁴

Affiliation:

1. Pharmacometrica; La Fouillade France

2. Massachusetts General Hospital; Boston Massachusetts USA

3. SUNY Upstate Medical University; Syracuse New York USA

4. Division of Quantitative Methods and Modeling, Office of Research and Standards, Office of Generic Drugs, Center for Drug Evaluation and Research; US Food and Drug Administration; Silver Spring Maryland USA

Funder

FDA

Publisher

Wiley

Subject

Pharmacology (medical),Pharmacology

Link

http://onlinelibrary.wiley.com/wol1/doi/10.1002/cpt.684/fullpdf

Reference44 articles.

1. Using mechanistic models to simulate comparative effectiveness trials of therapy and to estimate long-term outcomes in HIV care;Roberts;Med. Care,2010

2. Quantitative pharmacology approach in Alzheimer's disease: efficacy modeling of early clinical data to predict clinical outcome of tesofensine;Lehr;AAPS J,2010

3. Pharmacokinetic and pharmacodynamic basis for effective argatroban dosing in pediatrics;Madabushi;J. Clin. Pharmacol.,2011