Variabilities in commercial cyanotoxin standards

Author:

Jia Ai1ORCID,Prescott Matthew D.1,Guo Yingbo C.1,Di Giovanni George D.1,Li Wei L.1,Garcia Eduardo A.1,Zapata Jonathan1,Patton Samuel D.1ORCID,Vanderford Brett J.2,Eaton Andrew D.3ORCID

Affiliation:

1. Water Quality Section The Metropolitan Water District of Southern California La Verne California 91750 USA

2. Southern Nevada Water Authority Henderson Nevada 89015 USA

3. Eurofins Eaton Analytical, LLC Monrovia California 91016 USA

Abstract

AbstractCyanotoxin standards are commercially available from various suppliers. To investigate the potential impact of different sources on the comparability of cyanotoxin monitoring results among different methods and studies, this study evaluated the quality of 86 cyanotoxin standards from nine vendors via enzyme‐linked immunosorbent assay and liquid chromatography–tandem mass spectrometry. Substantial variabilities between vendors (up to 60%) and between lots (up to 98%) were observed for most of the standards. In addition, some of the microcystin standards had up to 11% of other microcystins as impurities. Compared to non‐certified analytical standards, certified standards showed much better agreement, with standards variations below 15% for all tested toxins. This study highlights the importance of developing and applying unified and certified standards for cyanotoxin analysis to improve the consistency and comparability of results. If different sources/lots of standards are used, they need to be cross‐checked to evaluate the potential impacts on results.

Funder

Water Research Foundation

Publisher

Wiley

Subject

Water Science and Technology,Environmental Engineering,General Chemistry,Filtration and Separation

Reference28 articles.

1. California Cyanobacteria and Harmful Algal Bloom (CCHAB). (2020).Appendix A‐description of cyanotoxin trigger levels in recreational water bodies.https://mywaterquality.ca.gov/monitoring_council/cyanohab_network/docs/2016/appendix_a_2016_1.pdf

2. Citriglia M. E. Agrawal S. G. Bhattacharyya D. Read R. A. Schordock D. C. Westrick J. &Birbeck J.(2019).Water Research Foundation project 4647 report. Evaluation and optimization of microcystin Analytical Methods.

3. Colorado Department of Public Health and Environment (CDPHE). (2020).Toxic algae risk management toolkit for recreational waters.https://cdphe.colorado.gov/toxic-algae

4. Cyanobacterial toxins: biosynthetic routes and evolutionary roots

5. Congener-Independent Immunoassay for Microcystins and Nodularins

Cited by 3 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370

www.globalauthorid.com

TOP

Copyright © 2019-2024 北京同舟云网络信息技术有限公司
京公网安备11010802033243号  京ICP备18003416号-3