Characterization of the AXH domain of Ataxin-1 using enhanced sampling and functional mode analysis-Reference-Cited by-同舟云学术

Characterization of the AXH domain of Ataxin-1 using enhanced sampling and functional mode analysis

Published:2016-03-09 Issue:5 Volume:84 Page:666-673
ISSN:0887-3585
Container-title:Proteins: Structure, Function, and Bioinformatics
language:en
Short-container-title:Proteins

Author:

Deriu Marco A.¹,Grasso Gianvito¹,Tuszynski Jack A.²,Massai Diana³⁴,Gallo Diego³,Morbiducci Umberto³,Danani Andrea¹

Affiliation:

1. Istituto Dalle Molle Di Studi Sull'intelligenza Artificiale (IDSIA), Scuola Universitaria Professionale Della Svizzera Italiana (SUPSI), Università Della Svizzera Italiana (USI); Centro Galleria 2 Manno CH-6928 Switzerland

2. Department of Physics; University of Alberta; Edmonton Alberta Canada

3. Department of Mechanical and Aerospace Engineering; Politecnico Di Torino; Corso Duca Degli Abruzzi 24 Torino IT-10128 Italy

4. Department of Cardiothoracic; Transplantation, and Vascular Surgery (HTTG), Leibniz Research Laboratories for Biotechnology and Artificial Organs (LEBAO), Hannover Medical School; Carl-Neuberg-Strabe 1 Hannover 30625 Germany

Funder

Swiss National Supercomputing Centre (CSCS)

Publisher

Wiley

Subject

Molecular Biology,Biochemistry,Structural Biology

Reference33 articles.

1. The structure of the AXH domain of spinocerebellar ataxin-1;Chen;J Biol Chem,2004

2. Pathogenic mechanisms of a polyglutamine-mediated neurodegenerative disease, Spinocerebellar ataxia type 1;Zoghbi;J Biol Chem,2009

3. The AXH module: an independently folded domain common to ataxin-1 and HBP1;Chiara;FEBS Lett,2003

4. The AXH domain adopts alternative folds the solution structure of HBP1 AXH;Chiara;Structure,2005

5. Polyglutamine Diseases and Neurodegeneration: The Example of Ataxin-1

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