Circadian lighting effect for inpatients with schizophrenia: A prospective cohort study

Author:

Tsai Ya‐Chi1ORCID,Jou Jwo‐Huei2,Hsu Ching‐Chi13ORCID,Shih Ming‐Chang2,The Luke2,Sharma Dipanshu2

Affiliation:

1. Department of International Intercollegiate PhD Program National Tsing Hua University Hsinchu Taiwan, ROC

2. Department of Materials Science and Engineering National Tsing Hua University Hsinchu Taiwan, ROC

3. Board of Directors, Wizcare Medical Corporation Aggregate Taichung Taiwan, ROC

Abstract

AbstractObjectivesIn schizophrenia, nonspecific lighting likely causes sleep timing disturbances, leading to distress and poorer clinical status. However, the effect of exposure to circadian lighting on psychopathology outcome in schizophrenia remains unknown. Hence, this study aimed to develop such an intervention and investigate its impact on schizophrenia.MethodsTwenty schizophrenia patients at a psychiatric nursing institute were monitored over 10 weeks, with assessments using the Brief Psychiatric Rating Scale (BPRS) and Mini‐Mental State Examination (MMSE) conducted at baseline, weeks 3 (T1), 7 (T2), and 10 (T3).ResultsCircadian lighting significantly improved BPRS scores between T1–T2 (p < .05) and T1–T3 (p < .001), with affectivity scores also showing significant enhancements postintervention. Notably, female participants exhibited substantial improvements in BPRS scores from T1 to T3 (p < .01), while male participants demonstrated significant gains in MMSE scores from T1 to T2 (p < .01).ConclusionsCircadian lighting presents a promising intervention for improving psychiatric outcomes in schizophrenia, with distinct benefits observed across different psychopathological aspects and genders. These findings underscore the potential of lighting chronotherapy in psychiatric clinical practice and warrant further exploration in related research.

Publisher

Wiley

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