Review of chemical models and applications in Geant4‐DNA: Report from the ESA BioRad III Project-Reference-Cited by-同舟云学术

Review of chemical models and applications in Geant4‐DNA: Report from the ESA BioRad III Project

Published:2024-06-18 Issue: Volume: Page:
ISSN:0094-2405
Container-title:Medical Physics
language:en
Short-container-title:Medical Physics

Author:

Tran Hoang Ngoc¹^ORCID,Archer Jay²^ORCID,Baldacchino Gérard³⁴,Brown Jeremy M. C.⁵,Chappuis Flore⁶,Cirrone Giuseppe Antonio Pablo⁷⁸^ORCID,Desorgher Laurent⁶,Dominguez Naoki⁹^ORCID,Fattori Serena⁷^ORCID,Guatelli Susanna²,Ivantchenko Vladimir¹⁰,Méndez José‐Ramos⁹,Nieminen Petteri¹¹,Perrot Yann¹²,Sakata Dousatsu²¹³¹⁴,Santin Giovanni¹¹,Shin Wook‐Geun¹⁵^ORCID,Villagrasa Carmen¹²,Zein Sara¹,Incerti Sebastien¹^ORCID

Affiliation:

1. Univ. Bordeaux CNRS, LP2I, UMR 5797 Gradignan France

2. Centre For Medical and Radiation Physics University of Wollongong Wollongong New South Wales Australia

3. Université Paris‐Saclay, CEA LIDYL Gif‐sur‐Yvette France

4. CY Cergy Paris Université, CEA LIDYL Gif‐sur‐Yvette France

5. Optical Sciences Centre Department of Physics and Astronomy School of Science Swinburne University of Technology Melbourne Australia

6. Institute of Radiation Physics (IRA) Lausanne University Hospital and University of Lausanne Lausanne Switzerland

7. Istituto Nazionale di Fisica Nucleare (INFN) Laboratori Nazionali del Sud (LNS) Catania Italy

8. Centro Siciliano di Fisica Nucleare e Struttura della Materia Catania Italy

9. Department of Radiation Oncology University of California San Francisco San Francisco California USA

10. CERN Geneva Switzerland

11. European Space Agency, ESTEC Noordwijk The Netherlands

12. Institut de Radioprotection et de Sûreté Nucléaire (IRSN) Fontenay‐aux‐Roses France

13. Division of Health Sciences Osaka University Osaka Japan

14. School of Physics University of Bristol Bristol UK

15. Physics Division Department of Radiation Oncology Massachusetts General Hospital & Harvard Medical School Boston Massachusetts USA

Abstract

AbstractA chemistry module has been implemented in Geant4‐DNA since Geant4 version 10.1 to simulate the radiolysis of water after irradiation. It has been used in a number of applications, including the calculation of G‐values and early DNA damage, allowing the comparison with experimental data. Since the first version, numerous modifications have been made to the module to improve the computational efficiency and extend the simulation to homogeneous kinetics in bulk solution. With these new developments, new applications have been proposed and released as Geant4 examples, showing how to use chemical processes and models. This work reviews the models implemented and application developments for modeling water radiolysis in Geant4‐DNA as reported in the ESA BioRad III Project.

Publisher

Wiley

Link

https://aapm.onlinelibrary.wiley.com/doi/pdf/10.1002/mp.17256

Reference79 articles.

1. Simulation of DNA Damage after Proton Irradiation

2. Cross sections for the interactions of 1 eV–100 MeV electrons in liquid water and application to Monte-Carlo simulation of HZE radiation tracks

3. Calculations of heavy-ion track structure

4. Monte Carlo Simulation of Water Radiolysis for Low-energy Charged Particles

5. Radiation track, DNA damage and response—a review