Glutathione antioxidant pathway activity and reserve determine toxicity and specificity of the biliary toxin biliatresone in zebrafish-Reference-Cited by-同舟云学术

Glutathione antioxidant pathway activity and reserve determine toxicity and specificity of the biliary toxin biliatresone in zebrafish

Published:2016-06-11 Issue:3 Volume:64 Page:894-907
ISSN:0270-9139
Container-title:Hepatology
language:en
Short-container-title:Hepatology

Author:

Zhao Xiao¹,Lorent Kristin¹,Wilkins Benjamin J.²,Marchione Dylan M.³,Gillespie Kevin³,Waisbourd-Zinman Orith⁴,So Juhoon⁵,Koo Kyung Ah⁶,Shin Donghun⁵,Porter John R.⁶,Wells Rebecca G.¹,Blair Ian³,Pack Michael¹⁷

Affiliation:

1. Division of Gastroenterology; Department of Medicine; Perelman School of Medicine; University of Pennsylvania; Philadelphia PA

2. Department of Pathology and Laboratory Medicine; Children's Hospital of Philadelphia; Philadelphia PA

3. Department of Systems Pharmacology and Translational Therapeutics; Perelman School of Medicine; University of Pennsylvania; Philadelphia PA

4. Division of Gastroenterology, Hepatology and Nutrition; Children's Hospital of Philadelphia; Philadelphia PA

5. Department of Developmental Biology; McGowan Institute for Regenerative Medicine; University of Pittsburgh; Pittsburgh PA

6. Department of Biological Sciences; University of the Sciences; Philadelphia PA

7. Department of Cell and Developmental Biology; Perelman School of Medicine; University of Pennsylvania; Philadelphia PA

Funder

NIH/NIDDK

Center for Molecular Studies in Digestive and Liver Diseases Pilot Grant

Fred and Suzanne Biesecker Pediatric Liver Center

Publisher

Wiley

Subject

Hepatology

Link

http://onlinelibrary.wiley.com/wol1/doi/10.1002/hep.28603/fullpdf

Reference44 articles.

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5. Genome-wide association study identifies a susceptibility locus for biliary atresia on 10q24.2;Garcia-Barcelo;Hum Mol Genet,2010

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