A five-CpG DNA methylation score to predict metastatic-lethal outcomes in men treated with radical prostatectomy for localized prostate cancer

Author:

Zhao Shanshan1,Leonardson Amy2,Geybels Milan S.23,McDaniel Andrew S.4,Yu Ming5,Kolb Suzanne2,Zong Hong5,Carter Kelly5,Siddiqui Javed4,Cheng Anqi2,Wright Jonathan L.26,Pritchard Colin C.7,Lance Raymond8,Troyer Dean9,Fan Jian-Bing10,Ostrander Elaine A.11,Dai James Y.2,Tomlins Scott A.4,Feng Ziding212,Stanford Janet L.213ORCID

Affiliation:

1. National Institute of Environmental Health Sciences; Biostatistics and Computational Biology Branch; Research Triangle Park; Durham North Carolina

2. Division of Public Health Sciences; Fred Hutchison Cancer Research Center; Seattle Washington

3. Department of Epidemiology; GROW School for Oncology and Developmental Biology; Maastricht University; Maastricht The Netherlands

4. Departments of Pathology and Urology; University of Michigan; Ann Arbor Michigan

5. Division of Clinical Research; Fred Hutchinson Cancer Research Center; Seattle Washington

6. Department of Urology; University of Washington School of Medicine; Seattle Washington

7. Department of Laboratory Medicine; University of Washington School of Medicine; Seattle Washington

8. Department of Urology; Eastern Virginia Medical School; Norfolk Virginia

9. Departments of Pathology, Microbiology, and Molecular Cell Biology; Eastern Virginia Medical School; Norfolk Virginia

10. Department of Oncology; Illumina, Inc.; San Diego California

11. Cancer Genetics and Comparative Genomics Branch; National Human Genome Research Institute; NIH; Bethesda Maryland

12. Department of Biostatistics; MD Anderson Cancer Center; Houston Texas

13. Department of Epidemiology; University of Washington School of Public Health; Seattle Washington

Publisher

Wiley

Subject

Urology,Oncology

Reference26 articles.

1. Who dies from prostate cancer;Patrikidou;Prostate Cancer Prostatic Dis,2014

2. Howlader N NA Krapcho M Garshell J 2013 http://seercancergov/csr/1975 2013

3. Temporal trends and the impact of race, insurance, and socioeconomic status in the management of localized prostate cancer;Gray;Eur Urol,2017

4. Cancer treatment and survivorship statistics, 2014;DeSantis;CA Cancer J Clin,2014

5. A critical analysis of the long-term impact of radical prostatectomy on cancer control and function outcomes;Boorjian;Eur Urol,2012

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