A large‐scale transcriptome‐wide association study (TWAS) of 10 blood cell phenotypes reveals complexities of TWAS fine‐mapping

Author:

Tapia Amanda L.1,Rowland Bryce T.1,Rosen Jonathan D.1,Preuss Michael2,Young Kris3,Graff Misa3,Choquet Hélène4,Couper David J.1,Buyske Steve5,Bien Stephanie A.6ORCID,Jorgenson Eric4,Kooperberg Charles6,Loos Ruth J. F.2,Morrison Alanna C.7,North Kari E.3,Yu Bing7,Reiner Alexander P.8,Li Yun1910ORCID,Raffield Laura M.9

Affiliation:

1. Department of Biostatistics University of North Carolina Chapel Hill North Carolina USA

2. The Charles Bronfman Institute for Personalized Medicine Icahn School of Medicine at Mount Sinai New York New York USA

3. Department of Epidemiology University of North Carolina Chapel Hill North Carolina USA

4. Division of Research Kaiser Permanente Northern California Oakland California USA

5. Department of Statistics Rutgers University Piscataway New Jersey USA

6. Division of Public Health Sciences Fred Hutchinson Cancer Research Center Seattle Washington USA

7. Department of Epidemiology, Human Genetics, and Environmental Sciences, Human Genetics Center, School of Public Health The University of Texas Health Science Center at Houston Houston Texas USA

8. Department of Epidemiology University of Washington Seattle Washington USA

9. Department of Genetics University of North Carolina Chapel Hill North Carolina USA

10. Department of Computer Science University of North Carolina at Chapel Hill Chapel Hill North Carolina USA

Funder

National Institute of Diabetes and Digestive and Kidney Diseases

National Institutes of Health

National Eye Institute

North Carolina Translational and Clinical Sciences Institute, University of North Carolina at Chapel Hill

National Heart, Lung, and Blood Institute

National Human Genome Research Institute

Publisher

Wiley

Subject

Genetics (clinical),Epidemiology

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