Determinants of suboptimal CD4 + T cell recovery after antiretroviral therapy initiation in a prospective cohort of acute HIV‐1 infection-Reference-Cited by-同舟云学术

Determinants of suboptimal CD4 + T cell recovery after antiretroviral therapy initiation in a prospective cohort of acute HIV‐1 infection

Published:2020-09 Issue:9 Volume:23 Page:
ISSN:1758-2652
Container-title:Journal of the International AIDS Society
language:en
Short-container-title:J Intern AIDS Soc

Author:

Handoko Ryan¹^ORCID,Colby Donn J²³^ORCID,Kroon Eugène²,Sacdalan Carlo²,Souza Mark²,Pinyakorn Suteeraporn²³⁴,Prueksakaew Peeriya²,Munkong Chutharat²,Ubolyam Sasiwimol⁵,Akapirat Siriwat⁶,Chiarella Jennifer¹,Krebs Shelly³⁴,Sereti Irini⁷,Valcour Victor⁸,Paul Robert⁹,Michael Nelson L.³,Phanuphak Nittaya²,Ananworanich Jintanat²³⁴,Spudich Serena¹,

Affiliation:

1. Yale School of Medicine New Haven CT USA

2. SEARCH The Thai Red Cross AIDS Research Centre Bangkok Thailand

3. United States Military HIV Research Program Walter Reed Army Institute of Research Silver Spring MD USA

4. The Henry M. Jackson Foundation for the Advancement of Military Medicine Bethesda MD USA

5. HIV‐NAT The Thai Red Cross AIDS Research Centre Bangkok Thailand

6. Armed Forces Research Institute of Medical Sciences US Army Medical Directorate Bangkok Thailand

7. Laboratory of Immunoregulation National Institute of Allergy and Infectious DiseasesNational Institutes of Health Bethesda MD USA

8. Memory and Aging Center Department of Neurology University of California San Francisco San Francisco CA USA

9. Missouri Institute of Mental Health University of Missouri‐St. Louis St. Louis MO USA

Funder

Merck

Gilead Sciences

ViiV Healthcare

U.S. Military HIV Research Program

National Institutes of Health

Division of Intramural Research, National Institute of Allergy and Infectious Diseases

Publisher

Wiley

Subject

Infectious Diseases,Public Health, Environmental and Occupational Health

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/jia2.25585

Reference41 articles.

1. The Absence of CD4+ T Cell Count Recovery Despite Receipt of Virologically Suppressive Highly Active Antiretroviral Therapy: Clinical Risk, Immunological Gaps, and Therapeutic Options

2. Enhanced CD4+ T-Cell Recovery with Earlier HIV-1 Antiretroviral Therapy

3. Long-term antiretroviral therapy initiated during primary HIV-1 infection is key to achieving both low HIV reservoirs and normal T cell counts

4. Risk of Severe Non AIDS Events Is Increased among Patients Unable to Increase their CD4+ T-Cell Counts >200+/μl Despite Effective HAART

5. Long-term Mortality in HIV-Positive Individuals Virally Suppressed for >3 Years With Incomplete CD4 Recovery

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