VGF and striatal cell damage in in vitro and in vivo models of Huntington's disease
Author:
Affiliation:
1. Molecular Pharmacology Department of Biofunctional Evaluation Gifu Pharmaceutical University 1‐25‐4 Daigaku‐nishi Gifu 501‐1196 Japan
2. Asubio Pharma Co., Ltd. 6‐4‐3, Minatojima‐Minamimachi, Chuo‐ku Kobe 650‐0047 Japan
Funder
Asubio Pharma Co., Ltd
Publisher
Wiley
Subject
General Pharmacology, Toxicology and Pharmaceutics,Neurology
Link
https://onlinelibrary.wiley.com/doi/pdf/10.1002/prp2.140
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4. The HD mutation causes progressive lethal neurological disease in mice expressing reduced levels of huntingtin
5. Early Striatal Dendrite Deficits followed by Neuron Loss with Advanced Age in the Absence of Anterograde Cortical Brain-Derived Neurotrophic Factor
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3. Reduced mitochondrial complex II activity enhances cell death via intracellular reactive oxygen species in STHdhQ111 striatal neurons with mutant huntingtin;Journal of Pharmacological Sciences;2021-12
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