Pharmacokinetic/Pharmacodynamic Evaluation of Ivosidenib or Enasidenib Combined With Intensive Induction and Consolidation Chemotherapy in Patients With Newly Diagnosed IDH1/2 ‐Mutant Acute Myeloid Leukemia
Author:
Affiliation:
1. Agios Pharmaceuticals, Inc. Cambridge Massachusetts USA
2. Current address: Servier Pharmaceuticals LLC Boston Massachusetts USA
Publisher
Wiley
Subject
Pharmacology (medical),Pharmaceutical Science
Link
https://onlinelibrary.wiley.com/doi/pdf/10.1002/cpdd.1067
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1. IDH mutations in cancer and progress toward development of targeted therapeutics
2. Isocitrate dehydrogenase mutations in myeloid malignancies
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5. Cancer-associated IDH1 mutations produce 2-hydroxyglutarate
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