Prognostic significance of CXCR4 expression in acute myeloid leukemia
Author:
Affiliation:
1. Center for Stem Cell Research and Application Union Hospital Tongji Medical College Huazhong University of Science and Technology Wuhan China
2. Neonatal Screening Center The Third Affiliated Hospital of Zhengzhou University Zhengzhou China
Funder
Hubei Provincial Natural Science Foundation of China
National Natural Science Foundation, P.R China
Publisher
Wiley
Subject
Cancer Research,Radiology, Nuclear Medicine and imaging,Oncology
Link
https://onlinelibrary.wiley.com/doi/pdf/10.1002/cam4.2535
Reference32 articles.
1. The SDF‐1‐CXCR4 Axis Stimulates VEGF Secretion and Activates Integrins but does not Affect Proliferation and Survival in Lymphohematopoietic Cells
2. Defects of B-cell lymphopoiesis and bone-marrow myelopoiesis in mice lacking the CXC chemokine PBSF/SDF-1
3. Functional response of leukaemic blasts to stromal cell-derived factor-1 correlates with preferential expression of the chemokine receptor CXCR4 in acute myelomonocytic and lymphoblastic leukaemia
4. CXCR4 antagonists: targeting the microenvironment in leukemia and other cancers
5. A phase 1/2 study of chemosensitization with the CXCR4 antagonist plerixafor in relapsed or refractory acute myeloid leukemia
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