Association Between Combined Presence of Hepatitis C Virus and Polymorphisms in Different Genes With Toxicities of Methotrexate and 6-Mercaptopurine in Children With Acute Lymphoblastic Leukemia

Author:

Abdelaziz Doaa H.1,Elhosseiny Noha M.2,Khaleel Sahar A.3,Sabry Nirmeen A.4,Attia Ahmed S.2,El-Sayed Manal H.5

Affiliation:

1. Department of Clinical Pharmacy; National Hepatology and Tropical Medicine Research Institute; Cairo Egypt

2. Department of Microbiology and Immunology; Faculty of Pharmacy; Cairo University; Cairo Egypt

3. Department of Pediatric Oncology; National Cancer Institute; Cairo University; Cairo Egypt

4. Department of Clinical Pharmacy; Faculty of Pharmacy; Cairo University; Cairo Egypt

5. Department of Pediatrics; Hematology-Oncology Division; Faculty of Medicine; Ain-Shams University; Cairo Egypt

Funder

Faculty of Pharmacy Cairo University, Egypt

Publisher

Wiley

Subject

Oncology,Hematology,Pediatrics, Perinatology and Child Health

Reference50 articles.

1. Hepatitis C virus (HCV) infection: A systemic disease;Craxi;Mol Aspects Med,2008

2. Treatment of childhood acute lymphoblastic leukemia;Stanulla;Semin Hematol,2009

3. The influence of detoxification agents on the intensity of side effects caused by medium-high doses of methotrexate in children with acute lymphoblastic leukemia: Case series;Šumar;Hosp Pharmacol,2014

4. Impact of genetic polymorphisms on chemotherapy toxicity in childhood acute lymphoblastic leukemia;Gervasini;Front Genet,2012

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