Determination of P‐glycoprotein inhibition by excipients and their combinations using an integrated high‐throughput process

Author:

Wang Szu‐Wen,Monagle Julie,McNulty Chris,Putnam David,Chen Hongming

Publisher

Elsevier BV

Subject

Pharmaceutical Science

Reference27 articles.

1. Multiple recognition of various amphiphilic molecules by the multidrug resistance P‐glycoprotein: Molecular mechanisms and pharmacological consequences coming from functional interactions between various drugs;Orlowski;Anticancer Res,1999

2. P‐glycoprotein: A defense mechanism limiting oral bioavailability and CNS accumulation of drugs;Fromm;Int J Clin Pharmacol Ther,2000

3. Intestinal secretion of drugs. The role of P‐glycoprotein and related drug efflux systems in limiting oral drug adsorption;Hunter;Adv Drug Delivery Rev,1997

4. Modulation and prevention of multidrug resistance by inhibitors of P‐glycoprotein;Sikic;Cancer Chemother Pharmacol,1997

5. The pharmacological role of P‐glycoprotein in the intestinal epithelium;Asperen;Pharmacol Res,1998

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