A Pragmatic, Randomized Controlled Trial of Oral Antivirals for the Treatment of Chronic Hepatitis C: The PRIORITIZE Study

Author:

Sulkowski Mark S.1ORCID,Moon Juhi S.1,Sherman Kenneth E.2ORCID,Morelli Giuseppe3,Darling Jama M.4,Muir Andrew J.5ORCID,Khalili Mandana6ORCID,Fishbein Dawn A.7,Hinestrosa Federico8,Shiffman Mitchell L.9,Di Bisceglie Adrian10,Rajender Reddy K.11,Pearlman Brian12,Lok Anna S.13,Fried Michael W.4,Stewart Paul W.14,Peter Joy3,Wadsworth Summer15,Kixmiller Scott16,Sloan Anquenette17,Vainorius Monika4,Horne Patrick M.3,Michael Larry14,Dong Meichen14,Evon Donna M.4,Segal Jodi B.18,Nelson David R.3,

Affiliation:

1. Division of Infectious Diseases Johns Hopkins University School of Medicine Baltimore MD

2. Department of Internal Medicine University of Cincinnati College of Medicine Cincinnati OH

3. Department of Gastroenterology, Hepatology & Nutrition University of Florida Gainesville FL

4. Division of Gastroenterology and Hepatology University of North Carolina at Chapel Hill Chapel Hill NC

5. Division of Gastroenterology Duke University Durham NC

6. Department of Medicine University of California San FranciscoZuckerberg San Francisco General, Hospital and Trauma Center San Francisco CA

7. Infectious Disease Medstar Health Research Institute Washington DC

8. Infectious Disease Orlando Immunology Center Orlando FL

9. Department of Gastroenterology Liver Institute of Virginia Richmond VA

10. Department of Internal Medicine Saint Louis University School of Medicine St. Louis MO

11. Department of Medicine University of Pennsylvania Philadelphia PA

12. Department of Internal Medicine Wellstar Health System Atlanta GA

13. Department of Internal Medicine University of Michigan Ann Arbor MI

14. Department of Biostatistics University of North Carolina at Chapel Hill, Chapel Hill, NC

15. PRIORITIZE Patient Engagement Group consultant Garner, NC

16. PRIORITIZE Patient Engagement Group consultant Greensboro, NC

17. PRIORITIZE Patient Engagement Group consultant Pittsboro, NC

18. Division of Internal Medicne Johns Hopkins University School of Medicine Baltimore MD

Funder

Patient-Centered Outcomes Research Institute

AbbVie

Merck

Publisher

Wiley

Subject

Hepatology

Reference31 articles.

1. Global prevalence and genotype distribution of hepatitis C virus infection in 2015: a modelling study;Polaris Observatory HCV Collaborators;Lancet Gastroenterol Hepatol,2015

2. Cure With Interferon‐Free Direct‐Acting Antiviral Is Associated With Increased Survival in Patients With Hepatitis C Virus‐Related Hepatocellular Carcinoma From Both East and West

3. Estimating Prevalence of Hepatitis C Virus Infection in the United States, 2013-2016

4. AASLD/IDSA HCV Guidance PanelRecommendations for testing managing and treating hepatitis C website. Published 2017. Accessed June 13 2017.http://hcvguidelines.org

5. Public–Private Partnership: Targeting Real-World Data for Hepatitis C Direct-Acting Antivirals

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