Structure comparison of native and mutant human recombinant FKBP12 complexes with the immunosuppressant drug FK506 (tacrolimus)

Author:

Itoh Susumu,Navia Manuel A.

Publisher

Wiley

Subject

Molecular Biology,Biochemistry

Reference36 articles.

1. Contributions of hydrogen bonds of Thr 157 to the thermodynamic stability of phage T4 lysozyme;Alber;Nature (Lond),1987

2. Charged surface residues of FKBP12 participate in formation of the FKBP12-FK506 calcineurin complex;Aldape;J Biol Chem,1992

3. Design, synthesis and structure of non-macrocyclic inhibitors of FKBP12, the major binding protein for the immunosuppressant FK506;Armistead;Acta Crystallogr,1995

4. FK-506-binding protein: Three dimensional structure of the complex with the antagonist L-685,818;Becker;J Biol Chem,1993

5. The Protein Data Bank: A computer-based archival file for macromolecular structures;Bernstein;J Mol Biol,1977

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