Substrate polarization by residues in Δ5-3-ketosteroid isomerase probed by site-directed mutagenesis and UV resonance Raman spectroscopy

Author:

Austin Janina C.,Spiro Thomas G.,Kuliopulos Athan,Mildvan Albert S.

Funder

NIH

Publisher

Wiley

Subject

Molecular Biology,Biochemistry

Reference37 articles.

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2. UV resonance Raman excitation profiles of the aromatic amino acids;Asher;J. Am. Chem. Soc.,1986

3. Evidence for an enol intermediate in the 3-oxo-Δ5-steroid isomerase catalysed isomerization of Δ5-ketones;Bantia;J. Am. Chem. Soc.,1986

4. Conformational flexibility in androgenic steroids: The structure of a new form of (+)-17b-hydroxy-19-nor-4-androstene-3-one (19-nortestosterone), C18H26O2;Bhadbhade;Acta Crystallogr.,1984

5. Secondary structure determination in proteins from deep (192-223 nm) ultraviolet Raman spectroscopy;Copeland;Biochemistry,1987

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