Prevalence of BRCA1 and BRCA2 pathogenic variants in a large, unselected breast cancer cohort

Author:

Li Jingmei123ORCID,Wen Wei Xiong4,Eklund Martin3,Kvist Anders5,Eriksson Mikael3,Christensen Helene Nordahl6,Torstensson Astrid6,Bajalica-Lagercrantz Svetlana7,Dunning Alison M.8,Decker Brennan8910,Allen Jamie8,Luccarini Craig8,Pooley Karen8,Simard Jacques11,Dorling Leila8ORCID,Easton Douglas F.8,Teo Soo-Hwang4,Hall Per3,Borg Åke5,Grönberg Henrik3,Czene Kamila3

Affiliation:

1. Human Genetics; Genome Institute of Singapore; Singapore Singapore

2. Department of Surgery; Yong Loo Lin School of Medicine, National University of Singapore; Singapore Singapore

3. Department of Medical Epidemiology and Biostatistics; Karolinska Institutet; Stockholm Sweden

4. Cancer Research Malaysia, Sime Darby Medical Centre; Subang Jaya Selangor Malaysia

5. Division of Oncology and Pathology, Department of Clinical Sciences; Lund University; Lund Sweden

6. AstraZeneca Nordic-Baltic; Södertälje Sweden

7. Department of Oncology-Pathology; Karolinska Universitetssjukhuset; Stockholm Sweden

8. Centre for Cancer Genetic Epidemiology; University of Cambridge; Cambridge United Kingdom

9. Cancer Genetics and Comparative Genomics Branch, National Human Genome Research Institute, National Institutes of Health; Bethesda MD

10. Department of Pathology; Brigham and Women's Hospital; Boston MA

11. Genomics Center, Centre Hospitalier Universitaire de Québec-Université Laval Research Center; Canada Research Chair in Oncogenetics, Université Laval; Quebec City Canada

Funder

Cancer Research UK

Cancerfonden

National Research Foundation Singapore

Alex och Eva Wallströms Stiftelse för Vetenskaplig Forskning och Utbildning

National Human Genome Research Institute

Intramural Research Program

Government of Canada

Linnaeus Centre

Cancer Risk Prediction Center

ALF Medicine

Forskningsrådet om Hälsa, Arbetsliv och Välfärd

Vetenskapsrådet

AstraZeneca

Publisher

Wiley

Subject

Cancer Research,Oncology

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