Profiling and identification of (−)-epicatechin metabolites in rats using ultra-high performance liquid chromatography coupled with linear trap-Orbitrap mass spectrometer

Author:

Shang Zhanpeng1ORCID,Wang Fei1,Dai Shengyun1,Lu Jianqiu2,Wu Xiaodan3,Zhang Jiayu4

Affiliation:

1. School of Chinese Pharmacy; Beijing University of Chinese Medicine; No. 6, Wang Jing Zhong Huan Nang Lu South Road, Wangjing, Chaoyang District Beijing 100102 China

2. Library of Beijing University of Chinese Medicine; Beijing University of Chinese Medicine; No. 11, Bei San Huan Dong Lu, Chaoyang District Beijing 100029 China

3. Department of Herbal Medicine, School of Basic Medical Sciences; Beijing University of Chinese Medicine; No. 11, Bei San Huan Dong Lu, Chaoyang District Beijing 100029 China

4. Beijing Research Institute of Chinese Medicine; Beijing University of Chinese Medicine; No. 11, Bei San Huan Dong Lu, Chaoyang District Beijing 100029 China

Funder

National Natural Science Foundation of China

Publisher

Wiley

Subject

Spectroscopy,Pharmaceutical Science,Environmental Chemistry,Analytical Chemistry

Reference34 articles.

1. The development of Research and Application of Chiral Drugs;Wu;Chin. J. Mod. Appl. Pharm.,2009

2. Present state of new chiral drug development and review in Japan;Shimazawa;J. Health. Sci.,2008

3. Kinetics of drug absorption, distribution, metabolism, and excretion;Nelson;J. Pharm. Sci.,1961

4. Quantification in patient urine samples of felbamate and three metabolites: acid carbamate and two mercapturic acids;Thompson;Epilepsia,1999

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