New benzothienopyrimidine derivatives as dual EGFR/ARO inhibitors: Design, synthesis, and their cytotoxic effect on MCF‐7 breast cancer cell line-Reference-Cited by-同舟云学术

New benzothienopyrimidine derivatives as dual EGFR/ARO inhibitors: Design, synthesis, and their cytotoxic effect on MCF‐7 breast cancer cell line

Published:2022-03-14 Issue:5 Volume:83 Page:1075-1096
ISSN:0272-4391
Container-title:Drug Development Research
language:en
Short-container-title:Drug Development Research

Author:

Sobh Eman A.¹^ORCID,Khalil Nadia A.²,Faggal Samar I.²,Hassan Marwa S. A.²

Affiliation:

1. Pharmaceutical Chemistry Department, Faculty of Pharmacy Menoufia University Menoufia Egypt

2. Pharmaceutical Organic Chemistry Department, Faculty of Pharmacy Cairo University Cairo Egypt

Publisher

Wiley

Subject

Drug Discovery

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/ddr.21934

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3. Design, synthesis and biological evaluation of certain CDK2 inhibitors based on pyrazole and pyrazolo[1,5-a] pyrimidine scaffold with apoptotic activity

4. Discovery of Benzo[g]quinazolin benzenesulfonamide derivatives as dual EGFR/HER2 inhibitors

5. ZD1839, a specific epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor, induces the formation of inactive EGFR/HER2 and EGFR/HER3 heterodimers and prevents heregulin signaling in HER2‐overexpressing breast cancer cells;Anido J.;Clinical Cancer Research,2003

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