Affiliation:
1. Cardiology and Rhythmology, St Josef‐Hospital Ruhr University Bochum Bochum Germany
2. Neurology, St Josef‐Hospital Ruhr University Bochum Bochum Germany
Abstract
AbstractBackgroundThe aim of this study was to examine the prevalence of abnormal P‐wave parameters in patients with thrombus and/or spontaneous echo contrast (SEC) in the left atrial appendage (LAA), and to identify P‐wave parameters particularly associated with thrombus and SEC formation.HypothesisWe presume a significant relationship of P‐wave parameters with thrombi and SEC.MethodsAll patients in whom a thrombus or SEC was detected in the LAA on transoesophageal echocardiography were included in this study. Patients at risk (CHA2DS2‐VASc Score ≥3) and routine transoesophageal echocardiography to exclude thrombi served as the control group. A detailed ECG analysis was performed.ResultsOf a total of 4062 transoesophageal echocardiographies, thrombi and SEC were detected in 302 patients (7.4%). Of these patients, 27 (8.9%) presented with sinus rhythm. The control group included 79 patients. There was no difference in mean CHA2DS2‐VASc score in the two groups (p = .182). A high prevalence of abnormal P‐wave parameters was detected in patients with thrombus/SEC. Indicators for the presence of thrombi or SEC in the LAA were P‐wave duration >118 ms (Odds ratio (OR) 3.418, Confidence interval (CI) 1.522–7.674, p < .001), P‐wave dispersion >40 ms (OR 2.521, CI 1.390–4.571, p < .001) and advanced interatrial block (OR 1.431, CI 1.033–1.984, p = .005).ConclusionOur study revealed that several P‐wave parameters are associated with thrombi and SEC in the LAA. The results may help identify patients who are at particularly high risk for thromboembolic events (e.g., in patients with embolic stroke of undetermined source).
Subject
Cardiology and Cardiovascular Medicine,General Medicine
Cited by
2 articles.
订阅此论文施引文献
订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献